Hydroxyurea

• Catalog No.: H8627
• CAS Number: 127-07-1
• M. F.: CH4N2O2
• M. W.: 76.05466
• Purity: ≥98% (TLC)

SYNONYMS

• Title: 羟基脲
• IUPAC name: hydroxyurea
• IUPAC Traditional name: hydroxyurea
• Synonyms: Hydroxycarbamide

DATABASE IDS

• EC Number: 204-821-7
• CAS Number: 127-07-1
• Beilstein Number: 1741548
• PubChem SID: 24278474
• MDL Number: MFCD00007943

PROPERTIES

• Purity: ≥98% (TLC)
• Gene Information: human ... CA1(759), CA2(760), CYP1A2(1544), RRM1(6240)
• Apperance: white powder
• Solubility: H2O: soluble50 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H361
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P281
• Risk Statements: 46-63
• RTECS: YT4900000
• Safety Statements: 53-36/37-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

包装
1, 5, 10, 25, 100 g in poly bottle
Biochem/physiol Actions
抗肿瘤剂。通过形成自由基硝基氧灭活核糖核苷还原酶，自由基硝基氧可结合到酶活性位点的酪氨酰自由基。这可阻断脱氧核苷酸的合成，从而抑制 DNA 合成，并且诱导细胞周期同步化或 S-期细胞死亡。