Biotinamidohexanoic acid N-hydroxysuccinimide ester

• Catalog No.: B2643
• CAS Number: 72040-63-2
• M. F.: C20H30N4O6S
• M. W.: 454.5404
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: 2,5-dioxopyrrolidin-1-yl 6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanoate
• IUPAC Traditional name: 2,5-dioxopyrrolidin-1-yl 6-{5-[(3aS,4S,6aR)-2-oxo-hexahydrothieno[3,4-d]imidazolidin-4-yl]pentanamido}hexanoate
• Synonyms: N-(+)-Biotinyl-6-aminocaproic acid N-succinimidyl ester; Succinimidyl 6-(biotinamido)hexanoate; N-Succinimidyl N-biotinyl-6-aminocaproate; (+)-Biotinamidocaproate N-hydroxysuccinimidyl ester; N-(+)-Biotinyl-6-aminohexanoic acid NHS ester

DATABASE IDS

• MDL Number: MFCD00065502
• Beilstein Number: 3577403
• CAS Number: 72040-63-2
• PubChem SID: 24891665

PROPERTIES

• Purity: ≥98% (TLC)
• Apperance: powder
• Solubility: H2O: ≤2 mg/mL (with sonication)
• Solubility: DMF: soluble50 mg/mL (Stable up to 2 months in dry DMF.)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Biotinylation reagent incorporating an aminocaproyl spacer. This can reduce the steric hindrance in binding avidin to some biotinylated compounds. Typically coupled to primary amine in the pH range 6.5-8.5.