Home > Compound List > Product Information
Oxytetracycline hydrochloride_Molecular_structure_CAS_2058-46-0)
Click picture or here to close

Oxytetracycline hydrochloride

Catalog No. O5875 Name Sigma Aldrich
CAS Number 2058-46-0 Website http://www.sigmaaldrich.com
M. F. C22H25ClN2O9 Telephone 1-800-521-8956
M. W. 496.8949 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 133341


土霉素 盐酸盐
IUPAC name
(4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC Traditional name
oxytetracycline hydrochloride


MDL Number MFCD00135815
PubChem SID 24898027
Beilstein Number 3853107
CAS Number 2058-46-0
EC Number 218-161-2


Purity ≥95% (HPLC)
Suitability suitable for 1694 per US EPA
Apperance yellow crystalline
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS QI8225000
German water hazard class 2


Description (English)
Oxytetracycline is a tetracycline analog isolated from the actinomycete streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycopasma bovis isolates2. Product O5875 is ≥95% (HPLC), crystalline.
Biochem/physiol Actions
Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.