Tetracycline hydrochloride

• Catalog No.: T7660
• CAS Number: 64-75-5
• M. F.: C22H25ClN2O8
• M. W.: 480.8955

SYNONYMS

• Title: 四环素 盐酸盐
• IUPAC name: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
• IUPAC Traditional name: tetracycline hydrochloride

DATABASE IDS

• PubChem SID: 24900468
• MDL Number: MFCD00078142
• CAS Number: 64-75-5
• Beilstein Number: 3844873
• EC Number: 200-593-8

PROPERTIES

• Impurities: endotoxin, tested
• Suitability: suitable for cell culture
• Apperance: powder
• Melting Point: 220-223 °C(lit.)
• Solubility: H2O: soluble10 mg/mL (as a stock solution. Stock solutions should be filtered sterilized and stored at -20°C. Stable at 37°C for 4 days.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: QI9100000
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (English)

Application
Used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems. Recommended for use in cell culture applications at 10 mg/L.
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information