Iodoacetamide

• Catalog No.: I1149
• CAS Number: 144-48-9
• M. F.: C2H4INO
• M. W.: 184.96373
• Purity: ≥99% (HPLC)

SYNONYMS

• Title: 碘代乙酰胺
• IUPAC name: 2-iodoacetamide
• IUPAC Traditional name: iodoacetamide

DATABASE IDS

• MDL Number: MFCD00008028
• CAS Number: 144-48-9
• Beilstein Number: 1739080
• EC Number: 205-630-1
• PubChem SID: 24278486

PROPERTIES

• Antion Traces: chloride (Cl-): ≤0.05%
• Antion Traces: sulfate (SO42-): ≤0.05%
• Cation Traces: Al: ≤0.0005%
• Cation Traces: Ca: ≤0.0005%
• Cation Traces: Cu: ≤0.0005%
• Cation Traces: Fe: ≤0.0005%
• Cation Traces: K: ≤0.005%
• Cation Traces: Mg: ≤0.0005%
• Cation Traces: NH4+: ≤0.05%
• Cation Traces: Na: ≤0.05%
• Cation Traces: Pb: ≤0.001%
• Cation Traces: Zn: ≤0.0005%
• Ignition Residue: ≤0.1%
• Impurities: ≤0.0005% Phosphorus (P)
• Impurities: ≤0.1% Insoluble matter
• Purity: ≥99% (HPLC)
• Quality Level: PREMIUM
• Melting Point: 92-95 °C(lit.)
• Solubility: H2O: soluble0.5 M, clear, colorless
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H317-H334-H413
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P301 + P310-P342 + P311
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-42/43-53
• RTECS: AC4200000
• Safety Statements: 22-36/37-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site.1 It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.2