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Penicillin G potassium salt_Molecular_structure_CAS_113-98-4)
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Penicillin G potassium salt

Catalog No. PENK Name Sigma Aldrich
CAS Number 113-98-4 Website http://www.sigmaaldrich.com
M. F. C16H17KN2O4S Telephone 1-800-521-8956
M. W. 372.48048 Fax
Purity Email
Storage Chembase ID: 102196

SYNONYMS

Title
青霉素 G 钾盐
IUPAC name
potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
IUPAC Traditional name
potassium benzylpenicillin(1-)
Synonyms
苄青霉素 钾盐

DATABASE IDS

EC Number 204-038-0
PubChem SID 24899067
CAS Number 113-98-4
Beilstein Number 3832841
MDL Number MFCD00036193

PROPERTIES

GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H317
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P280
Risk Statements 42/43
RTECS XH9700000
Safety Statements 36/37
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria
Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs) which inhibits peptidoglycan chain cross-lining. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
Application
Penicillin G is a narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G potassium salt is used to study murosomes of staphylococci1 and the penicillin-induced lysis of Streptococcus mutans2.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

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