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Adenosine 3′,5′-cyclic monophosphate_Molecular_structure_CAS_60-92-4)
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Adenosine 3′,5′-cyclic monophosphate

Catalog No. A9501 Name Sigma Aldrich
CAS Number 60-92-4 Website http://www.sigmaaldrich.com
M. F. C10H12N5O6P Telephone 1-800-521-8956
M. W. 329.205941 Fax
Purity ≥98.5% (HPLC) Email
Storage Chembase ID: 102121

SYNONYMS

Title
腺苷-3′,5′-环单磷酸
IUPAC name
(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-2-one
IUPAC Traditional name
cyclic adenosine monophosphate
Synonyms
环化腺苷酸
cAMP
腺苷环磷酸酯

DATABASE IDS

PubChem SID 24278245
CAS Number 60-92-4
Beilstein Number 52645
EC Number 200-492-9
MDL Number MFCD00005845

PROPERTIES

Purity ≥98.5% (HPLC)
Gene Information human ... OPRK1(4986)
Apperance white powder
Melting Point 260 °C (dec.)(lit.)
Solubility H2O: soluble10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS AU7357600
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (简体中文)
包装
1, 5, 25 g in poly bottle
Biochem/physiol Actions
环化腺苷酸依赖性蛋白激酶 (PKA) 的自然活化剂。cAMP 是一种重要的第二信使,并且在很多系统中与神经递质或激素诱导的受体激活相关。已有显示,cAMP/PKA 信号通路可抑制细胞增殖,诱导分化并导致细胞凋亡。

REFERENCES