Urotensin II rat

• Catalog No.: U7507
• M. F.: C77H102N18O20S2
• M. W.: 1663.87238
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: (4S)-4-{[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-{[(1S,2S)-1-carboxy-2-methylbutyl]carbamoyl}-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-4-{[(2S)-1-[(2S)-2-[(2S,3R)-3-hydroxy-2-{2-[(2S)-3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]acetamido}butanamido]propanoyl]pyrrolidin-2-yl]formamido}butanoic acid
• IUPAC Traditional name: (4S)-4-{[(4R,7S,10S,13S,16S,19R)-10-(4-aminobutyl)-16-benzyl-4-{[(1S,2S)-1-carboxy-2-methylbutyl]carbamoyl}-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-4-{[(2S)-1-[(2S)-2-[(2S,3R)-3-hydroxy-2-{2-[(2S)-3-(3H-imidazol-4-yl)-2-[(5-oxopyrrolidin-2-yl)formamido]propanamido]acetamido}butanamido]propanoyl]pyrrolidin-2-yl]formamido}butanoic acid

PROPERTIES

• Biological Source: synthetic
• Purity: ≥97% (HPLC)
• Gene Information: rat ... Uts2(29180)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Glp-His-Gly-Thr-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile [Disulfide Bridge: 8-13]
Biochem/physiol Actions
A neuroendocrine peptide of the CRF family that was originally isolated from fish brain but is also found in mammalian brain and spinal motor neurons. It is a potent vasoconstrictor. It may be a mediator of stress-induced anorexia.