Valinomycin

• Catalog No.: V0627
• CAS Number: 2001-95-8
• M. F.: C54H90N6O18
• M. W.: 1111.3218
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: (3S,6S,9S,12R,15S,18S,21R,24R,27S,30S,33R,36R)-6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nonakis(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
• IUPAC Traditional name: (3R,6R,9S,12S,15S,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
• Synonyms: Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid

DATABASE IDS

• MDL Number: MFCD00005114
• PubChem SID: 24900697
• CAS Number: 2001-95-8
• EC Number: 217-896-6
• Beilstein Number: 78657

PROPERTIES

• Purity: ≥90% (HPLC)
• Purity: ≥98% (TLC)
• Quality Level: PREMIUM
• Apperance: white solid
• Solubility: DMSO: ≥10 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H300 + H310
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P280-P301 + P310-P302 + P350-P310
• RID/ADR: UN 2811 6.1/PG 1
• Risk Statements: 27/28
• RTECS: YV9468000
• Safety Statements: 28-36/37-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information