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2′-Deoxyguanosine monohydrate_Molecular_structure_CAS_312693-72-4)
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2′-Deoxyguanosine monohydrate

Catalog No. D7145 Name Sigma Aldrich
CAS Number 312693-72-4 Website http://www.sigmaaldrich.com
M. F. C10H15N5O5 Telephone 1-800-521-8956
M. W. 285.2566 Fax
Purity 99-100% Email
Storage Chembase ID: 70207

SYNONYMS

Title
2′-Deoxyguanosine 一水合物
IUPAC name
2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one hydrate
IUPAC Traditional name
2-deoxyguanosine hydrate
Synonyms
9-(2-Deoxy-β-D-ribofuranosyl)guanine
Guanine-2′-deoxyriboside

DATABASE IDS

PubChem SID 24894083
Beilstein Number 39814
MDL Number MFCD00150760
CAS Number 312693-72-4

PROPERTIES

Purity 99-100%
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
Risk Statements 22
German water hazard class 3

DETAILS

Description (English)
Application
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

REFERENCES