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3-Acetylpyridine adenine dinucleotide_Molecular_structure_CAS_86-08-8)
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3-Acetylpyridine adenine dinucleotide

Catalog No. A5251 Name Sigma Aldrich
CAS Number 86-08-8 Website http://www.sigmaaldrich.com
M. F. C22H28N6O14P2 Telephone 1-800-521-8956
M. W. 662.437042 Fax
Purity ≥85% Email
Storage Chembase ID: 133288

SYNONYMS

IUPAC name
3-acetyl-1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-1λ5-pyridin-1-ylium
IUPAC Traditional name
3-acetyl-1-[(2R,3R,4S,5R)-5-[({[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl phosphonato}oxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1λ5-pyridin-1-ylium
Synonyms
APAD

DATABASE IDS

CAS Number 86-08-8
MDL Number MFCD00078882
PubChem SID 24890959

PROPERTIES

Purity ≥85%
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
APAD is an NAD analog with higher oxidation potential than NAD. It can substitute for NAD as a hydrogen-accepting cofactor in many dehydrogenase reactions; e.g. lactate dehydrogenase from Toxoplasma, Clonorchis, and Plasmodium, bacterial lipoamide dehydrogenase, as well as mammalian dehydrogenases. It can also act as a proton acceptor in various transhydrogenation reactions with NADH or NADPH.
Linkage
Analog of NAD

REFERENCES