[D-Trp6]-LH-RH

• Catalog No.: L9761
• CAS Number: 57773-63-4
• M. F.: C64H82N18O13
• M. W.: 1311.44868
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamide
• IUPAC Traditional name: triptorelin
• Synonyms: [D-Trp6]-Luteinizing hormone releasing hormone

DATABASE IDS

• MDL Number: MFCD00167541
• CAS Number: 57773-63-4

PROPERTIES

• Purity: ≥97% (HPLC)
• Gene Information: human ... GNRH1(2796)
• Apperance: powder
• GHS Signal Word: Danger
• GHS Hazard statements: H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 60
• Safety Statements: 53-22-36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2
Biochem/physiol Actions
Potent LH-RH agonist with enhanced biological activity due to its slower rate of degradation. Like [D-Lys6]-LH-RH, the D-Trp6 analog has been shown to be effective against cancers expressing the LH-RH receptor. However, unlike the D-Lys6 analog, it is generally used in the unconjugated form.