Berberine chloride form

• Catalog No.: B3251
• CAS Number: 633-65-8
• M. F.: C20H18ClNO4
• M. W.: 371.81422

SYNONYMS

• IUPAC name: 16,17-dimethoxy-5,7-dioxa-13λ^5-azapentacyclo[11.8.0.0^2,^1^0.0^4,^8.0^1^5,^2^0]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-13-ylium chloride
• IUPAC Traditional name: 16,17-dimethoxy-5,7-dioxa-13λ^5-azapentacyclo[11.8.0.0^2,^1^0.0^4,^8.0^1^5,^2^0]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-13-ylium chloride
• Synonyms: 黄连素

DATABASE IDS

• CAS Number: 633-65-8
• MDL Number: MFCD00011939
• PubChem SID: 24891691
• EC Number: 211-195-9
• Color Index Number: 75160
• Beilstein Number: 3836585

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 2

DETAILS

Description (English)

Application
Fluorescent stain for heparin in mast cells
Biochem/physiol Actions
An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5′-methoxyhydnocarpin (5′-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.