[des-Gly10, D-Ala6]-LH-RH ethylamide acetate salt hydrate

• Catalog No.: L4513
• M. F.: C58H84N16O15
• M. W.: 1245.38576
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide acetic acid hydrate
• IUPAC Traditional name: (2S)-1-[(2S)-5-carbamimidamido-2-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide acetic acid hydrate

DATABASE IDS

• MDL Number: MFCD11046043

PROPERTIES

• Purity: ≥97% (HPLC)
• Gene Information: mouse ... GNRH1(2796), GNRHR(2798)rat ... GNRH1(14714), GNRHR(14715)
• Apperance: powder
• GHS Signal Word: Danger
• GHS Hazard statements: H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 60
• Safety Statements: 53-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Glp-His-Trp-Ser-Tyr-Ala-Leu-Arg-Pro-NHEt
Biochem/physiol Actions
Potent LH-RH agonist in rats and mice; reversibly delays sexual maturation in rats, stimulates spawning activity in fish.