Spironolactone

• Catalog No.: S3378
• CAS Number: 52-01-7
• M. F.: C24H32O4S
• M. W.: 416.57348
• Purity: 97.0-103.0%

SYNONYMS

• IUPAC name: (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(acetylsulfanyl)-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan]-6'-ene-5,5'-dione
• IUPAC Traditional name: spironolactone
• Synonyms: 4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate; 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone

DATABASE IDS

• EC Number: 200-133-6
• PubChem SID: 24277736
• CAS Number: 52-01-7
• MDL Number: MFCD00082250

PROPERTIES

• Purity: 97.0-103.0%
• Gene Information: human ... HSD17B1(3292), NR3C2(4306)rat ... Ar(24208)
• Melting Point: 207-208 °C(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 60
• Safety Statements: 53-22-36/37/39-45
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. S3378.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.