(±)-Thalidomide

• Catalog No.: T144
• CAS Number: 50-35-1
• M. F.: C13H10N2O4
• M. W.: 258.2295
• Purity: ≥98%

SYNONYMS

• IUPAC name: 2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
• IUPAC Traditional name: thalidomide
• Synonyms: (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

DATABASE IDS

• MDL Number: MFCD00153873
• PubChem SID: 24278765
• CAS Number: 50-35-1
• EC Number: 200-031-1

PROPERTIES

• Purity: ≥98%
• Gene Information: human ... LITAF(9516), TNF(7124)mouse ... Nos2(18126)rat ... Nos1(24598)
• Apperance: white solid
• Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.6 mg/mL
• Solubility: DMSO: >20 mg/mL
• Solubility: H2O: insoluble
• Solubility: ethanol: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H312-H361
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P280-P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 46-61-21-25-62
• RTECS: TI4375000
• Safety Statements: 53-22-26-36/37/39-45
• Hazard Class: 6.1
• UN Number: 2811
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
(±)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α); inhibitor of angiogenesis; immunosuppressive; sedative; teratogen.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T144.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.