Cyproterone acetate

• Catalog No.: C3412
• CAS Number: 427-51-0
• M. F.: C24H29ClO4
• M. W.: 416.93766
• Purity: ≥98%

SYNONYMS

• IUPAC name: (1S,2S,3S,5R,11R,12S,15R,16S)-15-acetyl-9-chloro-2,16-dimethyl-6-oxopentacyclo[9.7.0.0^2,^8.0^3,^5.0^1^2,^1^6]octadeca-7,9-dien-15-yl acetate
• IUPAC Traditional name: cyproterone acetate
• Synonyms: 6-Chloro-1β,2β-dihydro-17-hydroxy-3′H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate

DATABASE IDS

• MDL Number: MFCD00864671
• CAS Number: 427-51-0
• PubChem SID: 24278309
• EC Number: 207-048-3

PROPERTIES

• Purity: ≥98%
• Gene Information: human ... AR(367)mouse ... Nr3c1(14815)rat ... Ar(24208)
• GHS Signal Word: Warning
• GHS Hazard statements: H312-H332-H351
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22-40
• RTECS: GZ2230000
• Safety Statements: 22-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Synthetic steroid; androgen antagonist; potent inhibitor of leukocyte migration through endothethial cell monolayers. Liver tumor promoter in experimental animal model.1 Liver tumor promotion appears to be female gender-specific, as formation of an active metabolite that forms DNA adducts.2
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C3412.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.