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Pyrantel (+)-tartrate salt_Molecular_structure_CAS_33401-94-4)
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Pyrantel (+)-tartrate salt

Catalog No. P7674 Name Sigma Aldrich
CAS Number 33401-94-4 Website http://www.sigmaaldrich.com
M. F. C15H20N2O6S Telephone 1-800-521-8956
M. W. 356.3941 Fax
Purity Email
Storage Chembase ID: 133130

SYNONYMS

IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid; 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine
IUPAC Traditional name
L(+)-tartaric acid; pyrantel
Synonyms
1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine

DATABASE IDS

MDL Number MFCD00216022
EC Number 251-501-8
CAS Number 33401-94-4

PROPERTIES

GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P301 + P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25
RTECS UW0249000
Safety Statements 45
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Application
Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock1. Pyrantel tartrate salt is used to study allosteric modulation of the neuronal nicotinic acetylcholine receptors (nAChRs)2.
Biochem/physiol Actions
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. This is a cholinesterase inhibitor. It causes spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors.

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