Pyrantel (+)-tartrate salt

• Catalog No.: P7674
• CAS Number: 33401-94-4
• M. F.: C15H20N2O6S
• M. W.: 356.3941

SYNONYMS

• IUPAC name: (2R,3R)-2,3-dihydroxybutanedioic acid; 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine
• IUPAC Traditional name: L(+)-tartaric acid; pyrantel
• Synonyms: 1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine

DATABASE IDS

• MDL Number: MFCD00216022
• EC Number: 251-501-8
• CAS Number: 33401-94-4

PROPERTIES

• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• RTECS: UW0249000
• Safety Statements: 45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
Pyrantel is used to study neuronal nicotinic receptors and has been is used to treat parasiticinfections in livestock1. Pyrantel tartrate salt is used to study allosteric modulation of the neuronal nicotinic acetylcholine receptors (nAChRs)2.
Biochem/physiol Actions
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.
Pyrantel is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. This is a cholinesterase inhibitor. It causes spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors.