Okadaic acid ammonium salt from Prorocentrum concavum

• Catalog No.: O8010
• CAS Number: 155716-06-6
• M. F.: C44H71NO13
• M. W.: 822.03344
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: ammonium (2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoate
• IUPAC Traditional name: ammonium (2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydrospiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoate
• Synonyms: OA

DATABASE IDS

• CAS Number: 155716-06-6
• MDL Number: MFCD00153856
• PubChem SID: 24898053

PROPERTIES

• Purity: ≥90% (HPLC)
• Apperance: white solid
• Solubility: H2O: soluble0.1 mg/mL
• Solubility: DMSO: soluble
• Solubility: ethanol: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H315-H331
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P261-P280-P301 + P310-P311
• Risk Statements: 23/24/25-38
• Safety Statements: 22-26-36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.