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2-Mercaptopurine

Catalog No. M6875 Name Sigma Aldrich
CAS Number 28128-19-0 Website http://www.sigmaaldrich.com
M. F. C5H4N4S Telephone 1-800-521-8956
M. W. 152.17706 Fax
Purity ≥95% Email
Storage Chembase ID: 104294

SYNONYMS

IUPAC name
9H-purine-2-thiol
IUPAC Traditional name
9H-purine-2-thiol
Synonyms
2-MP
2-Thiopurine
2-Purinethiol

DATABASE IDS

PubChem SID 24897120
CAS Number 28128-19-0
MDL Number MFCD00047145
EC Number 248-855-0

PROPERTIES

Purity ≥95%
Apperance yellow crystalline
GHS Pictograms GHS05
GHS Pictograms GHS07
GHS Signal Word Danger
GHS Hazard statements H302-H318
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P280-P305 + P351 + P338
Risk Statements 22-41
Safety Statements 26-39
German water hazard class 3

DETAILS

Description (English)
Application
2-Mercaptopurine (2-MP), a thiopurine and analog of the anti-cancer drug 6-mercaptopurine (6-MP), has been used to study the substrate and binding specificity and kinetics of xanthine oxidase-catalyzed hydroxylation and myeloperoxidase (MPO) reactions. 2-Mercaptopurine inhibited lipopolysacharide (LPS)-dependent nitric oxide (NO) production in B cells.

REFERENCES