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Casein Kinase I substrate_Molecular_structure_CAS_154444-97-0)
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Casein Kinase I substrate

Catalog No. C2335 Name Sigma Aldrich
CAS Number 154444-97-0 Website http://www.sigmaaldrich.com
M. F. C85H139N27O35S Telephone 1-800-521-8956
M. W. 2131.23806 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 133100

SYNONYMS

IUPAC name
(4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]hexanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carboxypropanamido]-4-carboxybutanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S,2R)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}ethyl]carbamoyl}butanoic acid
IUPAC Traditional name
(4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]hexanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carboxypropanamido]-4-carboxybutanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S,2R)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}ethyl]carbamoyl}butanoic acid

DATABASE IDS

MDL Number MFCD00672412
CAS Number 154444-97-0

PROPERTIES

Compostion Peptide content, ~70%
Potency 172 μM Km
Purity ≥95% (HPLC)
Gene Information rat ... Ppp1r2(192361)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Arg-Arg-Lys-Asp-Leu-His-Asp-Asp-Glu-Glu-Asp-Glu-Ala-Met-Ser-Ile-Thr-Ala
Specificity
Vmax with casein kinase-1 is 6-fold higher than for casein. Rate of phosphorylation by casein kinase-2 is negligible.

REFERENCES