Casein Kinase I substrate

• Catalog No.: C2335
• CAS Number: 154444-97-0
• M. F.: C85H139N27O35S
• M. W.: 2131.23806
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]hexanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carboxypropanamido]-4-carboxybutanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S,2R)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}ethyl]carbamoyl}butanoic acid
• IUPAC Traditional name: (4S)-4-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]hexanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carboxypropanamido]-3-carboxypropanamido]-4-carboxybutanamido]-4-carboxybutanamido]-3-carboxypropanamido]-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S,2S)-1-{[(1S,2R)-1-{[(1S)-1-carboxyethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-methylbutyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}ethyl]carbamoyl}butanoic acid

DATABASE IDS

• MDL Number: MFCD00672412
• CAS Number: 154444-97-0

PROPERTIES

• Compostion: Peptide content, ~70%
• Potency: 172 μM Km
• Purity: ≥95% (HPLC)
• Gene Information: rat ... Ppp1r2(192361)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
Arg-Arg-Lys-Asp-Leu-His-Asp-Asp-Glu-Glu-Asp-Glu-Ala-Met-Ser-Ile-Thr-Ala
Specificity
Vmax with casein kinase-1 is 6-fold higher than for casein. Rate of phosphorylation by casein kinase-2 is negligible.