Pituitary adenylate cyclase activating polypeptide-27 ovine

• Catalog No.: A9808
• CAS Number: 127317-03-7
• M. F.: C142H224N40O39S
• M. W.: 3147.60756
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: 3-[(1-{[1-({1-[(1-{[1-({1-[(5-amino-1-{[1-({1-[(1-{[1-({5-amino-1-[(5-amino-1-{[1-({1-[(1-{[1-({1-[(1-carbamoyl-3-methylbutyl)carbamoyl]-2-methylpropyl}carbamoyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl)carbamoyl]pentyl}carbamoyl)-2-methylpropyl]carbamoyl}ethyl)carbamoyl]-3-(methylsulfanyl)propyl}carbamoyl)-3-carbamoylpropyl]carbamoyl}pentyl)carbamoyl]-4-carbamimidamidobutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-4-carbamimidamidobutyl)carbamoyl]-2-hydroxyethyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-hydroxyethyl)carbamoyl]-3-[2-(2-{2-[2-(2-{2-[2-amino-3-(1H-imidazol-5-yl)propanamido]-3-hydroxypropanamido}-3-carboxypropanamido)acetamido]-3-methylpentanamido}-3-phenylpropanamido)-3-hydroxybutanamido]propanoic acid
• IUPAC Traditional name: 3-[(1-{[1-({1-[(1-{[1-({1-[(5-amino-1-{[1-({1-[(1-{[1-({5-amino-1-[(5-amino-1-{[1-({1-[(1-{[1-({1-[(1-carbamoyl-3-methylbutyl)carbamoyl]-2-methylpropyl}carbamoyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl)carbamoyl]pentyl}carbamoyl)-2-methylpropyl]carbamoyl}ethyl)carbamoyl]-3-(methylsulfanyl)propyl}carbamoyl)-3-carbamoylpropyl]carbamoyl}pentyl)carbamoyl]-4-carbamimidamidobutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-4-carbamimidamidobutyl)carbamoyl]-2-hydroxyethyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-hydroxyethyl)carbamoyl]-3-[2-(2-{2-[2-(2-{2-[2-amino-3-(3H-imidazol-4-yl)propanamido]-3-hydroxypropanamido}-3-carboxypropanamido)acetamido]-3-methylpentanamido}-3-phenylpropanamido)-3-hydroxybutanamido]propanoic acid
• Synonyms: PACAP-27

DATABASE IDS

• PubChem SID: 24891501
• CAS Number: 127317-03-7
• MDL Number: MFCD00167418

PROPERTIES

• Compostion: Peptide content, ~70%
• Purity: ≥97% (HPLC)
• Gene Information: human ... ADCY1(107)mouse ... ADCY1(432530)rat ... ADCY1(305509)sheep ... PACAP(443337)
• Apperance: white solid
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Amino Acid Sequence
His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
Biochem/physiol Actions
Neuropeptide that stimulates both adenylate cyclase in cultured pituitary cells and insulin release from pancreatic islet β-cells. Increases cAMP levels; increases tyrosine hydroxylase expression in chromaffin cells.