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Apramycin sulfate salt_Molecular_structure_CAS_65710-07-8)
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Apramycin sulfate salt

Catalog No. A2024 Name Sigma Aldrich
CAS Number 65710-07-8 Website http://www.sigmaaldrich.com
M. F. C21H43N5O15S Telephone 1-800-521-8956
M. W. 637.65562 Fax
Purity ~95% (TLC) Email
Storage Chembase ID: 133030


IUPAC name
(2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
IUPAC Traditional name
apramycin; sulfuric acid
Nebramycin II


MDL Number MFCD06200257
CAS Number 65710-07-8
EC Number 265-890-7


Purity ~95% (TLC)
GHS Pictograms GHS07
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H315-H319-H360
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P201-P305 + P351 + P338-P308 + P313
Risk Statements 61-36/38
Safety Statements 53-26-45
Storage Temperature 2-8°C
German water hazard class 3


Description (English)
Apramycin is used to study antibiotic resistance 1,2 as well as protein synthesis translocation-step inhibition in bacteria and prokaryotes.
Apramycin is used to study protein synthesis translocation-step inhibition in bacteria and prokaryotes.
Biochem/physiol Actions
Apramycin inhibits protein synthesis by blocking translocation. It is also able to bind to the eukaryotic decoding site 3.