Apramycin sulfate salt

• Catalog No.: A2024
• CAS Number: 65710-07-8
• M. F.: C21H43N5O15S
• M. W.: 637.65562
• Purity: ~95% (TLC)

SYNONYMS

• IUPAC name: (2R,3R,4S,5S,6S)-2-{[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}-4-hydroxy-3-(methylamino)-octahydropyrano[3,2-b]pyran-2-yl]oxy}-5-amino-6-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
• IUPAC Traditional name: apramycin; sulfuric acid
• Synonyms: Nebramycin II

DATABASE IDS

• MDL Number: MFCD06200257
• CAS Number: 65710-07-8
• EC Number: 265-890-7

PROPERTIES

• Purity: ~95% (TLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H319-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P305 + P351 + P338-P308 + P313
• Risk Statements: 61-36/38
• Safety Statements: 53-26-45
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Apramycin is used to study antibiotic resistance 1,2 as well as protein synthesis translocation-step inhibition in bacteria and prokaryotes.
Apramycin is used to study protein synthesis translocation-step inhibition in bacteria and prokaryotes.
Biochem/physiol Actions
Apramycin inhibits protein synthesis by blocking translocation. It is also able to bind to the eukaryotic decoding site 3.