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Hygromycin B from Streptomyces hygroscopicus_Molecular_structure_CAS_31282-04-9)
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Hygromycin B from Streptomyces hygroscopicus

Catalog No. H9773 Name Sigma Aldrich
CAS Number 31282-04-9 Website http://www.sigmaaldrich.com
M. F. C20H37N3O13 Telephone 1-800-521-8956
M. W. 527.52008 Fax
Purity ≥60% (HPAE) Email
Storage Chembase ID: 133018

SYNONYMS

Title
潮霉素 B 来源于吸水链霉菌
IUPAC name
(2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
IUPAC Traditional name
(2S,3'R,3aS,4S,4'S,5'R,6R,6'R,7S,7aS)-4-{[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy}-6'-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)-tetrahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol

DATABASE IDS

MDL Number MFCD06795479
CAS Number 31282-04-9
EC Number 250-545-5

PROPERTIES

Purified By ion-exchange chromatography
Purity ≥60% (HPAE)
Suitability plant cell culture tested
Apperance lyophilized powder
GHS Pictograms GHS05
GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Signal Word Danger
GHS Hazard statements H300 +H310 + H330-H318-H334
European Hazard Symbols Highly toxic Highly toxic (T+)
GHS Precautionary statements P260-P264-P280-P284-P301 + P310-P302 + P350
RID/ADR UN 3462 6.1/PG 1
Risk Statements 26/27/28-41-42/43
RTECS WK2130000
Safety Statements 22-26-28-36/37/39-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 3462
Packing Group 1
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Mode of Action: Blocks polypeptide synthesis and inhibits elongation. For use in the selection and maintenance of prokaryotic and eukaryotic cells.
Application
Hygromycin B is used in molecular biology as a selection agent for plant cells transformed with selectable marker genes such as hygromycin phosphotransferase (hpt).
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

REFERENCES