Melatonin

• Catalog No.: M5250
• CAS Number: 73-31-4
• M. F.: C13H16N2O2
• M. W.: 232.27834
• Purity: ≥98% (TLC)

SYNONYMS

• Title: 褪黑素
• IUPAC name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
• IUPAC Traditional name: melatonin
• Synonyms: N-乙酰基-5-甲氧基色胺

DATABASE IDS

• PubChem SID: 24278103
• MDL Number: MFCD00005655
• EC Number: 200-797-7
• CAS Number: 73-31-4
• Beilstein Number: 205542

PROPERTIES

• Purity: ≥98% (TLC)
• Gene Information: human ... MTNR1A(4543), MTNR1B(4544), NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)
• Apperance: off-white powder
• Melting Point: 116.5-118 °C(lit.)
• Solubility: H2O: soluble0.1 mg/mL
• Solubility: ethanol: soluble8 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: AC5955000
• Storage Temperature: -20°C
• German water hazard class: 2

DETAILS

Description (简体中文)

Caution
Solutions are light sensitive and subject to oxidation.
包装
1, 5, 10 g in glass bottle
250 mg in glass bottle
Biochem/physiol Actions
Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5250.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.