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trans-4-Hydroxy-L-proline_Molecular_structure_CAS_51-35-4)
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trans-4-Hydroxy-L-proline

Catalog No. H5534 Name Sigma Aldrich
CAS Number 51-35-4 Website http://www.sigmaaldrich.com
M. F. C5H9NO3 Telephone 1-800-521-8956
M. W. 131.12986 Fax
Purity ≥98.5% Email
Storage Chembase ID: 91182

SYNONYMS

Title
L-羟基脯氨酸
IUPAC name
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
IUPAC Traditional name
hypro
Synonyms
Hydroxyproline
(2S,4R)-4-羟基吡咯烷-2-羧酸
Hyp
4-Hydroxyproline

DATABASE IDS

CAS Number 51-35-4
EC Number 200-091-9
PubChem SID 24895700
Beilstein Number 81441
MDL Number MFCD00064320

PROPERTIES

Impurities endotoxin, tested
Purity ≥98.5%
Suitability suitable for cell culture
Melting Point 273 °C (dec.)(lit.)
Solubility H2O: soluble50 mg/mL
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (简体中文)
Other Notes
动物结构蛋白(如胶原和弹性蛋白)的天然成分。
包装
10 mg in autosmp vl
Biochem/physiol Actions
Hydroxyproline (4-hydroxyproline) is a non-proteinogenic amino acid formed by the post-translational hydroxylation of proline. Hydroxyproline is a major component of collagen, where it serves to stabilize the helical structure. Because hydroxyproline is largely restricted to collagen, the measurement of hydroxylproline levels can be used as an indicator of collagen content. Conditions that increase collagen turnover can elevate serum and urine hydroxyproline levels. Urine and serum hydroxyproline levels can be used as a marker for bone resorption.

REFERENCES