Cytosine β-D-arabinofuranoside

• Catalog No.: C1768
• CAS Number: 147-94-4
• M. F.: C9H13N3O5
• M. W.: 243.21662
• Purity: ≥90% (HPLC)

SYNONYMS

• Title: 胞嘧啶 β-D-呋喃阿拉伯糖苷
• IUPAC name: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: cytarabine
• Synonyms: Ara-C; 阿拉伯糖胞嘧啶; 阿糖胞苷; (β-D-阿拉伯呋喃糖基)胞嘧啶; 胞嘧啶阿拉伯糖苷; 阿糖胞嘧啶

DATABASE IDS

• EC Number: 205-705-9
• MDL Number: MFCD00066487
• CAS Number: 147-94-4
• Beilstein Number: 89175
• PubChem SID: 24892435

PROPERTIES

• Purity: ≥90% (HPLC)
• Gene Information: human ... POLB(5423)mouse ... Cda(72269)
• Apperance: crystalline
• GHS Signal Word: Warning
• GHS Hazard statements: H317-H361
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280
• Risk Statements: 63-43
• RTECS: HA5425000
• Safety Statements: 36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
阿糖胞苷复合到 DNA 中后，可通过与导致 DNA 断裂的拓扑异构酶 I 形成可裂解复合物而抑制 DNA 的复制，但不会抑制 RNA 的合成。抗白血病制剂。