Coenzyme A hydrate

• Catalog No.: C4282
• CAS Number: 85-61-0(anhydrous)
• M. F.: C21H38N7O17P3S
• M. W.: 785.549403
• Purity: ≥85% (UV, HPLC)

SYNONYMS

• Title: 辅酶 A 水合物
• IUPAC name: {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid hydrate
• IUPAC Traditional name: coenzym A hydrate
• Synonyms: CoA

DATABASE IDS

• Beilstein Number: 77809
• CAS Number: 85-61-0(anhydrous)
• MDL Number: MFCD06795839
• PubChem SID: 24892684

PROPERTIES

• Purity: ≥85% (UV, HPLC)
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Caution
游离酸不及其钠盐或锂盐稳定；当储存在 -20°C 时在 6 个月内可降解 5%。
Biochem/physiol Actions
Coenzyme A (CoA) is an essential metabolic cofactor synthesized from cysteine, pantothenate, and ATP. CoA plays important roles in many metabolic pathways, including the tricarboxylic acid cycle, and the synthesis and oxidation of fatty acids. One of the main functions of CoA is the carrying and transfer of acyl groups. Acylated deriviates, for example acetyl-CoA, are critical intermediates in many metabolic reactions. CoA levels can be altered during starvation, and in conditions such as cancer, diabetes, and alcoholism.