Cholesteryl hemisuccinate tris salt

• Catalog No.: C6013
• CAS Number: 102601-49-0
• M. F.: C35H61NO7
• M. W.: 607.86134

SYNONYMS

• Title: 胆固醇琥珀酸单酯 三羟甲基氨基甲烷盐
• IUPAC name: 2-amino-2-(hydroxymethyl)propane-1,3-diol; 4-{[(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-5-yl]oxy}-4-oxobutanoic acid
• IUPAC Traditional name: 4-{[(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-5-yl]oxy}-4-oxobutanoic acid; tris buffer
• Synonyms: CHEMS; 胆固醇半琥珀酸酯; 3β-Hydroxy-5-cholestene 3-hemisuccinate; CHS; 胆甾醇琥珀酸酯

DATABASE IDS

• MDL Number: MFCD00058298
• CAS Number: 102601-49-0

PROPERTIES

• German water hazard class: 3

DETAILS

Description (English)

Application
Cholesteryl hemisuccinate (CHEMS) is a membrane stabilizer for liposomes.1 CHEMS improves the stability of membrane protein synaptogyrin-1.2 It has been used as a component of a folate-modified self-microemulsifying drug delivery system.3 Detergent blends with n-dodecyl β-D-maltoside (DDM) and CHEMS has been used to solubilize erythrocyte ghosts4 and chemokine receptor CCR1.5