Zardaverine

• Catalog No.: Z3003
• CAS Number: 101975-10-4
• M. F.: C12H10F2N2O3
• M. W.: 268.2162064

SYNONYMS

• IUPAC name: 6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one
• IUPAC Traditional name: zardaverine
• Synonyms: 6-(4-Difluoromethoxy-3-methoxyphenyl)-3(2H)-pyridazinone

DATABASE IDS

• PubChem SID: 24278784
• CAS Number: 101975-10-4
• MDL Number: MFCD00867059

PROPERTIES

• Potency: 1.1 μM IC50 (for PDE IV)
• Potency: 2.5 μM IC50 (for PDE III)
• Gene Information: human ... PDE3A(5139), PDE3B(5140), PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144), PDE5A(8654), PDE7A(5150)rat ... Pde2a(81743), Pde4a(25638)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Selective inhibitor of phosphodiesterase III/IV (PDE3/4).1