5-Azacytidine

• Catalog No.: A1287
• CAS Number: 320-67-2
• M. F.: C8H12N4O5
• M. W.: 244.20468

SYNONYMS

• Title: 5-氮杂胞嘧啶核苷
• IUPAC name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
• IUPAC Traditional name: azacitidine
• Synonyms: 阿扎胞苷; 4-氨基-1-(β-D-呋喃核糖基)-1,3,5-三嗪-2(1H)-酮

DATABASE IDS

• PubChem SID: 24890525
• Beilstein Number: 620461
• MDL Number: MFCD00006539
• CAS Number: 320-67-2
• EC Number: 206-280-2

PROPERTIES

• Grade: Hybri-Max™
• Impurities: endotoxin, tested
• Sterility: γ-irradiated
• Suitability: suitable for hybridoma
• Apperance: lyophilized powder
• Melting Point: 226-232 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P308 + P313
• Risk Statements: 45-46-22
• RTECS: XZ3017500
• Safety Statements: 22-36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Used to study the effects of the DNA incorporated molecule on DNA methylation processes.
Reconstitution
10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。最终工作浓度：10μM 5-氮杂胞嘧啶核苷。
Biochem/physiol Actions
一种强效生长抑制剂及细胞毒素剂，抑制 DNA 甲基转移酶，一种基因表达、基因激活和沉默的重要调节机制。
法律信息
Hybri-Max 商标 Sigma-Aldrich Co. LLC