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Acetylsalicylic acid

Catalog No. A5376 Name Sigma Aldrich
CAS Number 50-78-2 Website http://www.sigmaaldrich.com
M. F. C9H8O4 Telephone 1-800-521-8956
M. W. 180.15742 Fax
Purity ≥99.0% Email
Storage Chembase ID: 821

SYNONYMS

Title
乙酰水杨酸
IUPAC name
2-(acetyloxy)benzoic acid
IUPAC Traditional name
aspirin
Synonyms
2-乙酰氧基苯甲酸
ASA
O-乙酰基水杨酸
阿斯匹林

DATABASE IDS

Beilstein Number 779271
MDL Number MFCD00002430
EC Number 200-064-1
PubChem SID 24278218
CAS Number 50-78-2

PROPERTIES

Purity ≥99.0%
Gene Information human ... ITGA2B(3674), ITGB3(3690), PTGS1(5742), PTGS2(5743)
Absorption Wavelength ε1mM/230 nm, aqueous acid 466
Absorption Wavelength ε1mM/231 nm, aqueous base 409
Absorption Wavelength ε1mM/278 nm, aqueous acid 68
Absorption Wavelength ε1mM/298 nm, aqueous base 190
pKa 3.5
Apperance white crystalline
Flash Point 250 °C
Flash Point 482 °F
Melting Point 134-136 °C(lit.)
Solubility H2O: soluble10 mg/mL at 37 °C
Solubility H2O: soluble3 mg/mL at 25 °C
Solubility ethanol: soluble50 mg/mL
Solubility aqueous base: decomposes
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
RTECS VO0700000
Safety Statements 26
German water hazard class 1

DETAILS

Description (简体中文)
Frequently Asked Questions
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Biochem/physiol Actions
通过抑制环加氧酶(前列腺素 H 合成酶)来阻断前列腺素的生成,对 COX-1 亚型具有较高的选择性。可抑制血小板中的 COX-1,从而阻断血栓素的生成和血小板凝集,因此具有抗血栓形成的作用。针对结直肠和其他实体瘤的化学防治剂。
包装
1 kg in poly bottle
100, 250, 500 g in poly bottle

REFERENCES