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8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt_Molecular_structure_CAS_51116-01-9)
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8-Bromoguanosine 3′,5′-cyclic monophosphate sodium salt

Catalog No. B1381 Name Sigma Aldrich
CAS Number 51116-01-9 Website http://www.sigmaaldrich.com
M. F. C10H10BrN5NaO7P Telephone 1-800-521-8956
M. W. 446.083231 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 131320

SYNONYMS

IUPAC name
sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-6,9-dihydro-1H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-2-olate
IUPAC Traditional name
sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-1H-purin-9-yl)-7-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-2-olate
Synonyms
8-Br-cGMP
8-Bromo-cyclic GMP

DATABASE IDS

PubChem SID 24278021
CAS Number 51116-01-9
MDL Number MFCD00070128
EC Number 256-993-8

PROPERTIES

Purity ≥98% (HPLC)
Apperance powder
Solubility H2O: soluble50 mg/mL
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Cell-permeable cGMP analog having greater resistance to hydrolysis by phosphodiesterases than cGMP. Activates cGMP-dependent protein kinase. Slows or inhibits the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine. Reported to mimic the effect of nitric oxide generating drugs.

REFERENCES