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Ketorolac tris salt_Molecular_structure_CAS_74103-07-4)
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Ketorolac tris salt

Catalog No. K1136 Name Sigma Aldrich
CAS Number 74103-07-4 Website http://www.sigmaaldrich.com
M. F. C19H24N2O6 Telephone 1-800-521-8956
M. W. 376.40366 Fax
Purity ≥99% Email
Storage Chembase ID: 72775

SYNONYMS

IUPAC name
2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
IUPAC Traditional name
ketorolac; tris buffer
Synonyms
Toradol
(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt

DATABASE IDS

PubChem SID 24278503
CAS Number 74103-07-4
MDL Number MFCD00887595

PROPERTIES

Purity ≥99%
Gene Information human ... PTGS1(5742)
Apperance crystalline
Solubility H2O: soluble15 mg/mL (stable at least one month at -20 °C.)
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301-H315-H319-H335
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P261-P301 + P310-P305 + P351 + P338
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25-36/37/38
RTECS UY7759900
Safety Statements 26-45
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.

REFERENCES