Ketorolac tris salt

• Catalog No.: K1136
• CAS Number: 74103-07-4
• M. F.: C19H24N2O6
• M. W.: 376.40366
• Purity: ≥99%

SYNONYMS

• IUPAC name: 2-amino-2-(hydroxymethyl)propane-1,3-diol; 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
• IUPAC Traditional name: ketorolac; tris buffer
• Synonyms: Toradol; (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt

DATABASE IDS

• PubChem SID: 24278503
• CAS Number: 74103-07-4
• MDL Number: MFCD00887595

PROPERTIES

• Purity: ≥99%
• Gene Information: human ... PTGS1(5742)
• Apperance: crystalline
• Solubility: H2O: soluble15 mg/mL (stable at least one month at -20 °C.)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H315-H319-H335
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25-36/37/38
• RTECS: UY7759900
• Safety Statements: 26-45
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Non-steroidal anti-inflammatory agent and cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. Inhibits the induction of nitric oxide synthase by lipopolysaccharide in a murine macrophage cell line. Part of its analgesic effect may be due to the release of opioid peptides.
Caution
Stable at least 2 years if stored at room temperature.