TTNPB

• Catalog No.: T3757
• CAS Number: 71441-28-6
• M. F.: C24H28O2
• M. W.: 348.47792

SYNONYMS

• IUPAC name: 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid
• IUPAC Traditional name: ttnpb
• Synonyms: Arotinoid acid; 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid

DATABASE IDS

• MDL Number: MFCD00673917
• PubChem SID: 24278733
• CAS Number: 71441-28-6

PROPERTIES

• Gene Information: human ... RARA(5914), RARB(5915), RARG(5916), RXRA(6256), RXRB(6257), RXRG(6258)
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H319-H335-H360
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P261-P305 + P351 + P338-P308 + P313
• Risk Statements: 60-61-36/37/38
• RTECS: DH6834900
• Safety Statements: 53-26-36/37/39-45
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Selective and highly potent retinoic acid analog with affinity for retinoic acid receptors (RAR) α, β, and γ, which are nuclear transcription factors. Produces ligand-activated transcription of genes that possess retinoic acid responsive elements.