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Ebselen

Catalog No. E3520 Name Sigma Aldrich
CAS Number 60940-34-3 Website http://www.sigmaaldrich.com
M. F. C13H9NOSe Telephone 1-800-521-8956
M. W. 274.17666 Fax
Purity Email
Storage Chembase ID: 105101

SYNONYMS

IUPAC name
2-phenyl-2,3-dihydro-1,2-benzoselenazol-3-one
IUPAC Traditional name
ebselen
Synonyms
2-Phenyl-1,2-benzisoselenazol-3(2H)-one

DATABASE IDS

MDL Number MFCD00210937
CAS Number 60940-34-3
PubChem SID 24278417

PROPERTIES

GHS Pictograms GHS06
GHS Pictograms GHS08
GHS Pictograms GHS09
GHS Signal Word Danger
GHS Hazard statements H301-H331-H373-H410
European Hazard Symbols Toxic Toxic (T)
European Hazard Symbols Nature polluting Nature polluting (N)
GHS Precautionary statements P261-P273-P301 + P310-P311-P501
RID/ADR UN 3283 6.1/PG 3
Risk Statements 23/25-33-50/53
Safety Statements 20/21-28-45-60-61
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 3283
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
An organo-selenium compound possessing antioxidant properties. Inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol.1 Inhibits oxidation of low density lipoproteins (LDL).

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