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GBR 12935 dihydrochloride_Molecular_structure_CAS_67469-81-2)
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GBR 12935 dihydrochloride

Catalog No. G9659 Name Sigma Aldrich
CAS Number 67469-81-2 Website http://www.sigmaaldrich.com
M. F. C28H36Cl2N2O Telephone 1-800-521-8956
M. W. 487.50424 Fax
Purity ≥98% (TLC) Email
Storage Chembase ID: 132859

SYNONYMS

IUPAC name
1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
IUPAC Traditional name
1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
Synonyms
1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

DATABASE IDS

CAS Number 67469-81-2
MDL Number MFCD00083175
PubChem SID 24277959

PROPERTIES

Purity ≥98% (TLC)
Apperance white powder
Solubility H2O: soluble20 mg/mL (with warming)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Inhibits the dopamine and norepinephrine transporters with Kis of 21.5 nM and 225 nM, respectively. Does not inhibit the serotonin transporter (Ki = 6.5 μM). Binds to a nondopaminergic piperazine site in blood platelets and brain that has been identified as cytochrome P450.

REFERENCES