U-69593

• Catalog No.: U103
• CAS Number: 96744-75-1
• M. F.: C22H32N2O2
• M. W.: 356.50168

SYNONYMS

• IUPAC name: N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
• IUPAC Traditional name: N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
• Synonyms: U69593; (+)-(5α,7α,8β)-N-Methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-benzeneacetamide

DATABASE IDS

• MDL Number: MFCD05664586
• CAS Number: 96744-75-1
• PubChem SID: 24278769

PROPERTIES

• Gene Information: human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)mouse ... Oprk1(18387)rat ... Oprd1(24613), Oprk1(29335), Oprm1(25601)
• Apperance: white solid
• Optical Rotation: [α]/D +7.8°, c = 0.825 in methanol(lit.)
• Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble10 mg/mL
• Solubility: 0.1 M HCl: >40 mg/mL
• Solubility: ethanol: >40 mg/mL
• Solubility: 0.1 M NaOH: insoluble
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
U-69593 is a selective κ opioid receptor agonist.