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Ketanserin (+)-tartrate salt_Molecular_structure_CAS_83846-83-7)
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Ketanserin (+)-tartrate salt

Catalog No. S006 Name Sigma Aldrich
CAS Number 83846-83-7 Website http://www.sigmaaldrich.com
M. F. C26H28FN3O9 Telephone 1-800-521-8956
M. W. 545.5136232 Fax
Purity ≥97% Email
Storage Chembase ID: 132715


IUPAC name
(2R,3R)-2,3-dihydroxybutanedioic acid; 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1,2,3,4-tetrahydroquinazoline-2,4-dione
IUPAC Traditional name
L(+)-tartaric acid; ketanserin
R 41468 (+)-tartrate salt
3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt


EC Number 281-062-8
CAS Number 83846-83-7
MDL Number MFCD00084651
PubChem SID 24278121


Purity ≥97%
Gene Information human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
Apperance white solid
Solubility ethanol: soluble3.3 mg/mL
Solubility DMSO: soluble52 mg/mL
Solubility 0.1 M HCl: soluble6 mg/mL
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H301
European Hazard Symbols Toxic Toxic (T)
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P301 + P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25
RTECS VA1411195
Safety Statements 22-36/37/39-45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3


Description (English)
Biochem/physiol Actions
Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.1