β-Nicotinamide adenine dinucleotide phosphate hydrate

• Catalog No.: N5755
• CAS Number: 53-59-8(anhydrous)
• M. F.: C21H30N7O18P3
• M. W.: 761.420283
• Purity: ≥95% (HPLC)

SYNONYMS

• Title: β-Nicotinamid-adenin-dinucleotid-phosphorsäure 水合物
• IUPAC name: 1-[(2R,3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1λ^5-pyridin-1-ylium hydrate
• IUPAC Traditional name: nadp zwitterion hydrate
• Synonyms: Triphosphopyridinnucleotid; NADP; β-NADP; Coenzyme II; TPN

DATABASE IDS

• PubChem SID: 24897747
• MDL Number: MFCD10567218
• CAS Number: 53-59-8(anhydrous)

PROPERTIES

• Cation Traces: sodium and potassium: ≤0.04%
• Purity: ≥95% (HPLC)
• Purity: ≥95% (enzymatic)
• Purity: ≥95% (spectrophotometric assay)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Electron acceptor
Other Notes
Packaged based on solid weight.
This is a common form of NADP.
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).