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Guanosine 5′-triphosphate sodium salt hydrate_Molecular_structure_CAS_36051-31-7)
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Guanosine 5′-triphosphate sodium salt hydrate

Catalog No. G8877 Name Sigma Aldrich
CAS Number 36051-31-7 Website http://www.sigmaaldrich.com
M. F. C10H13N5Na3O14P3 Telephone 1-800-521-8956
M. W. 589.125913 Fax
Purity ≥95% (HPLC) Email
Storage Chembase ID: 132652


IUPAC name
trisodium {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl (phosphonatooxy)phosphonate
IUPAC Traditional name
trisodium [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl phosphonatooxyphosphonate


CAS Number 36051-31-7
PubChem SID 24895354
Beilstein Number 3585677
MDL Number MFCD00077781


Purity ≥95% (HPLC)
Shipped in dry ice
Gene Information human ... HRAS(3265)
Apperance white powder
Solubility H2O: soluble50 mg/mL
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3


Description (English)
Preparation Note
Prepared by enzymatic phosphorylation of 5′-GMP.
Biochem/physiol Actions
GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.