Uricase from Arthrobacter globiformis

• Catalog No.: U7128
• CAS Number: 9002-12-4
• M. F.: C18H26N5O14P
• M. W.: 567.397901

SYNONYMS

• IUPAC name: {[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic acid amine
• IUPAC Traditional name: [5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[5-(2,4-dioxo-3H-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyphosphinic acid amine
• Synonyms: Urate oxidase; Urate:O2 oxidoreductase

DATABASE IDS

• EC Number: 232-655-5
• CAS Number: 9002-12-4
• PubChem SID: 24900663
• Enzyme Commission Number: 1.7.3.3 ( BRENDA
• MDL Number: MFCD00082126
• Enzyme Commission Number: IUBMB )

PROPERTIES

• Apperance: lyophilized powder
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: YU7100000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Unit Definition
One unit will convert 1.0 μmole of uric acid to allantoin per min at pH 9.0 at 25 °C.
Biochem/physiol Actions
Molecular weight: 4 × ~32 KDa (tetramer)Isoelectric point: is 4.64KM value (uric acid as substrate): ~ 0.01 mM The optimum pH for activity: 8.5-9.5The optimum pH for stability: 6.0-9.5