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Sphingosine 1-phosphate

Catalog No. S9666 Name Sigma Aldrich
CAS Number 26993-30-6 Website http://www.sigmaaldrich.com
M. F. C18H38NO5P Telephone 1-800-521-8956
M. W. 379.471781 Fax
Purity ≥95% Email
Storage Chembase ID: 129593


IUPAC name
{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phosphonic acid
IUPAC Traditional name
sphingosine 1-phosphate
D-erythro-Sphingosine 1-phosphate
(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-phosphate


PubChem SID 24899853
CAS Number 26993-30-6
MDL Number MFCD00270077


Purity ≥95%
Quality Level PREMIUM
Gene Information human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637)
Apperance powder
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
Storage Temperature -20°C
German water hazard class 3


Description (English)
Biochem/physiol Actions
A lipid second messenger that binds to S1P1 and S1P3 receptors. Mobilizes intracellular Ca2+ stores and decreases cellular cAMP. Activates phospholipase D. S1P stimulates the migration of endothelial cells but inhibits the migration of other cell types. Induces angiogenesis.