β-D-Allose

• Catalog No.: A6390
• CAS Number: 7283-09-2
• M. F.: C6H12O6
• M. W.: 180.15588

SYNONYMS

• Title: β-D-阿洛糖
• IUPAC name: (2R,3R,4R,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
• IUPAC Traditional name: β-D-allose
• Synonyms: β-D-别吡喃糖

DATABASE IDS

• MDL Number: MFCD00063268
• PubChem SID: 24891083
• CAS Number: 7283-09-2

PROPERTIES

• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (简体中文)

包装
10 mg in autosmp vl
Application
β-D-Allose (β-D-Allose), a rare sugar member of the aldohexose family and a C3 epimer of glucose, is used as an inhibitor of fruiting body formation and sporulation in Myxococcus xanthus.
Biochem/physiol Actions
D-Allose is a rare aldohexose sugar that has demonstrated anti-cancer, antitumor, anti-inflammatory, anti-oxidative, antihypertensive, cryoprotective, and immunosuppressant activities.1 D-Allose upregulates thioredoxin-interacting protein (TXNIP) gene expression and was found to induce G1 cell cycle arrest in hepatocellular carcinoma cells.2 It inhibited transcriptional activity of the activator protein 1, nuclear factor-κB, and nuclear factor of activated T cells.3 D-Allose decreases transport of 2-deoxy-D-glucose and 3-O-methyl-D-glucose in V79 Chinese hamster lung fibroblast cells.4