(Z)-4-Hydroxytamoxifen

• Catalog No.: H7904
• CAS Number: 68047-06-3
• M. F.: C26H29NO2
• M. W.: 387.51396
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
• IUPAC Traditional name: 4-hydroxytamoxifen
• Synonyms: (Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol; trans-4-Hydroxytamoxifen; (Z)-4-OHT

DATABASE IDS

• PubChem SID: 24895814
• MDL Number: MFCD00278780
• CAS Number: 68047-06-3

PROPERTIES

• Purity: ≥98% (HPLC)
• Quality Level: PREMIUM
• Gene Information: human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)rat ... Ar(24208), Esr1(24890), Esr2(25149)
• Apperance: powder
• Solubility: methanol: soluble10 mg/mL
• Solubility: ethanol: soluble20 mg/mL (with heating)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332-H361
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280
• Risk Statements: 63-20/21/22
• RTECS: SL1210000
• Safety Statements: 22-23-36
• Storage Condition: desiccated
• Storage Condition: protect from light
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

General description
4-Hydroxytamoxifen is the active metabolite of tamoxifen which binds estrogen receptors (ER) and estrogen-related receptors (ERR) with estrogenic and anti-estrogenic effects. It is a selective estrogen receptor modulator (SERM).
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H7904.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.