4-Hydroxytamoxifen

• Catalog No.: H6278
• CAS Number: 68392-35-8
• M. F.: C52H58N2O4
• M. W.: 775.02792
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• Title: 4-羟基他莫西芬
• IUPAC name: 4-[(1E)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol; 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
• IUPAC Traditional name: 4-[(1E)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol; 4-hydroxytamoxifen
• Synonyms: (Z)-4-(1-[4-(二甲氨基乙氧基)苯基]-2-苯基-1-丁烯基)苯酚; 4-OHT; (Z)-4-羟基三苯氧胺

DATABASE IDS

• CAS Number: 68392-35-8
• PubChem SID: 24895736

PROPERTIES

• Purity: ≥98% (HPLC)
• Quality Level: PREMIUM
• Gene Information: human ... ESR1(2099), ESR2(2100), ESRRG(2104), IL6(3569)rat ... Ar(24208), Esr1(24890), Esr2(25149)
• Apperance: powder
• Solubility: methanol: soluble10 mg/mL
• Solubility: ethanol: soluble20 mg/mL (with heating)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332-H361
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280
• Risk Statements: 63-20/21/22
• RTECS: SL1210000
• Safety Statements: 22-23-36
• Storage Condition: desiccated
• Storage Condition: protect from light
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
化疗药物他莫西芬的代谢物，表现出比原药更强效的雌激素激动剂/拮抗剂活性。还是脂质过氧化的活性膜内抑制剂。