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Amphotericin B solubilized_Molecular_structure_CAS_1397-89-3)
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Amphotericin B solubilized

Catalog No. A9528 Name Sigma Aldrich
CAS Number 1397-89-3 Website http://www.sigmaaldrich.com
M. F. C47H73NO17 Telephone 1-800-521-8956
M. W. 924.07902 Fax
Purity Email
Storage Chembase ID: 132590


IUPAC name
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
IUPAC Traditional name
amphotericin B


Beilstein Number 78342
CAS Number 1397-89-3
PubChem SID 24891468
MDL Number MFCD00877763


Quality Level PREMIUM
Sterility γ-irradiated
Suitability suitable for cell culture
Apperance powder
Solubility sterile water: soluble20 mg/mL (as a stock solution. Stock solutions should be stored at -20 °C. Stable at 37 °C for 3 days.)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
Safety Statements 26
Storage Temperature 2-8°C
German water hazard class 3


Description (简体中文)
Frequently Asked Questions
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Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Biochem/physiol Actions
Mode of Action: Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out. Antimicrobial spectrum: fungi and yeast.
Package size based on amphotericin B
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information