Amphotericin B solubilized

• Catalog No.: A9528
• CAS Number: 1397-89-3
• M. F.: C47H73NO17
• M. W.: 924.07902

SYNONYMS

• IUPAC name: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19Z,21Z,23Z,25Z,27Z,29Z,31Z,33R,35S,36R,37S)-33-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
• IUPAC Traditional name: amphotericin B
• Synonyms: Fungizone

DATABASE IDS

• Beilstein Number: 78342
• CAS Number: 1397-89-3
• PubChem SID: 24891468
• MDL Number: MFCD00877763

PROPERTIES

• Quality Level: PREMIUM
• Sterility: γ-irradiated
• Suitability: suitable for cell culture
• Apperance: powder
• Solubility: sterile water: soluble20 mg/mL (as a stock solution. Stock solutions should be stored at -20 °C. Stable at 37 °C for 3 days.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Biochem/physiol Actions
Mode of Action: Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.
Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out. Antimicrobial spectrum: fungi and yeast.
包装
Package size based on amphotericin B
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information