Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt

• Catalog No.: C8271
• CAS Number: 3063-71-6
• M. F.: C20H30N4NaO16P
• M. W.: 636.432931
• Purity: ≥85% (HPLC)

SYNONYMS

• IUPAC name: sodium [(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,4S,5R)-2-carboxy-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl phosphate
• IUPAC Traditional name: sodium [(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,4S,5R)-2-carboxy-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl phosphate
• Synonyms: CMP-NeuAc; CMP-NANA; CMP-NAN; CMP-Sialic acid

DATABASE IDS

• CAS Number: 3063-71-6
• MDL Number: MFCD00151579
• Beilstein Number: 4224251
• PubChem SID: 24893038

PROPERTIES

• Purity: ≥85% (HPLC)
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Substrate for sialyltransferases. Used for the enzymatic sialylation of glycans.
Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.
Preparation Note
Enzymatically prepared by the method of Schauer, R., et al., Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972).CMP-NAN is very acid-labile.