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Uroguanylin

Catalog No. U5131 Name Sigma Aldrich
CAS Number 154525-25-4 Website http://www.sigmaaldrich.com
M. F. C64H102N18O26S4 Telephone 1-800-521-8956
M. W. 1667.85968 Fax
Purity ≥90% (HPLC) Email
Storage Chembase ID: 132559

SYNONYMS

IUPAC name
(2S)-2-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-25-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-carboxypropanamido]-3-carboxypropanamido]-10-(carbamoylmethyl)-22-(2-carboxyethyl)-32-[(1R)-1-hydroxyethyl]-4-methyl-19-(2-methylpropyl)-3,6,9,12,15,18,21,24,30,33,36-undecaoxo-7,13-bis(propan-2-yl)-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetracontan-38-yl]formamido}-4-methylpentanoic acid
IUPAC Traditional name
(2S)-2-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-25-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-carboxypropanamido]-3-carboxypropanamido]-10-(carbamoylmethyl)-22-(2-carboxyethyl)-32-[(1R)-1-hydroxyethyl]-7,13-diisopropyl-4-methyl-19-(2-methylpropyl)-3,6,9,12,15,18,21,24,30,33,36-undecaoxo-27,28,40,41-tetrathia-2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetracontan-38-yl]formamido}-4-methylpentanoic acid
Synonyms
Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu [Disulfide bridges: 4–12, 7–15]

DATABASE IDS

MDL Number MFCD00237307
CAS Number 154525-25-4

PROPERTIES

Purity ≥90% (HPLC)
Gene Information human ... GUCA2B(2981)
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu [Disulfide bridges: 4–12, 7–15]
Biochem/physiol Actions
Stimulates intestinal guanylate cyclase.

REFERENCES