Amoxicillin

• Catalog No.: A8523
• CAS Number: 26787-78-0
• M. F.: C16H19N3O5S
• M. W.: 365.40416

SYNONYMS

• Title: 阿莫西林
• IUPAC name: (2S,5R,6R)-6-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• IUPAC Traditional name: amoxicillin

DATABASE IDS

• Beilstein Number: 7507120
• MDL Number: MFCD00056860
• EC Number: 248-003-8
• CAS Number: 26787-78-0

PROPERTIES

• Potency: ≥900 μg per mg
• Solubility: Do you have solubility information on this product that you would like to share?
• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XH8300000
• Safety Statements: 22-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Application
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Amoxicillin is a moderate-spectrum, β-lactam antibiotic . Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of polymorphonuclear leukocytes (PMNLs), the risk of resistance development in Helicobacter pylor, and various dosing strategies against Streptococcus pneumoniae and Pneumococcal pneumonia 1,2,3,4. It is also used to study the synthesis of bacterial cell walls at the level of peptidoglycan polymer chain cross-linking involving bacterial transpeptidase.
Amoxicillin is used to study the synthesis of bacterial cell walls at the level of peptidoglycan polymer chain cross-linking involving bacterial transpeptidase.
Biochem/physiol Actions
Amoxicillin inhibits the synthesis of bacterial cell walls. It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls of both Gram-positive and Gram-negative bacteria.